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Description

Tirzepatide: SURMOUNT-1 (72 Weeks) The SURMOUNT-1 trial enrolled 2,539 adults with obesity (BMI 30) or overweight with comorbidities

P = 0.1666 ( Ri- Mp FER ), 0.1384 ( Ri- Mp LLG )

Inflammation 40 , 861870 (2017)

The bone effects of amylin analogues also deserve investigation, as these drugs not only bind the amylin receptors AMY1R, AMY2R, and AMY3R, but also the calcitonin receptor, raising the possibility of direct effects on bone metabolism [10]