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Both compounds are among the most researched peptides for tissue repair and recovery, and the combination is studied for synergistic effects on healing speed, angiogenesis, and musculoskeletal recovery

A 2024 randomized trial found that a single high dose reduced the decline in processing speed and memory during overnight sleep deprivation, with a smaller effect in rested people

HUBERMAN: So for instance, the peptide Sirmirelin, which promotes the release of growth hormone has been FDA approved for the treatment of short stature, but it is often now prescribed for other things as well, where a physician and their patient agree

It is important to note that this concern is entirely theoretical -- no oncological adverse effects have been reported in the limited preclinical studies -- but the biological plausibility is high enough to warrant serious consideration