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Patients can simply use one pen each week, which makes treatment planning more predictable

The drawbacks are real but limited

Molecular Specifications: Molecular Weight: 4845.444 g/mol Molecular Formula: CHNO CAS Number : 2381089-83-2 Peptide Sequence : H-Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Val-Ile-Ala-Gln-Val-Glu-Leu-Leu-Leu-Trp-Leu-Val-Ile-Ser-Gly-Leu-Gln-Arg-Leu-Gly-Gly-Gly-Pro-Pro-Pro-Ser-NH2 Structure: Single peptide conjugated to a C20 fatty diacid moiety for extended half-life (approximately 6 days), enabling once-weekly administration Receptor Potency Profile

Benjamin Natelson, to apply (successfully) for three successive seed grants from the CFIDS Association of America (now Solve ME/CFS Initiative) to investigate, using brain MRI/MRS, whether mitochondrial dysfunction was responsible for the elevations of ventricular lactate that wed observed in ME/CFS [Mathew et al 2009, Murrough et al 2010, Shungu et al 2012]