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Call Your Provider Promptly For Severe abdominal pain (possible pancreatitis) Persistent vomiting that prevents fluid intake Right-upper-quadrant pain that radiates to the back or shoulder (possible gallbladder issue) Sudden vision changes (rare, but reported) Symptoms of severe dehydration: dizziness on standing, dark urine, dry mouth For a deeper dive on what to expect over time, our side effect timeline guide walks through duration and management for each common issue

In a related context, a large retrospective cohort study using real-world surgical data found no significant association between preoperative GLP-1 RA use and 30-day postoperative aspiration pneumonia 51

Reapply every 2-3 hours if outdoors