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[3] [4] [27] Hyperammonemia with and without encephalopathy has been observed in patients who were taking topiramate

The main ionizable chelators mentioned: Citric acid a tetra dentate chelator, EDTA (Ethylene diamine tetraacetic acid) an hexa dentate chelator, DTPA (Diethylenetriamine pentaacetic acid) octa dentate chelator

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