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Hypoglycemia risk Although the risk of hypoglycemia with these medications is generally low, combining them could potentially increase this risk, especially in patients also taking insulin or sulfonylureas

Management of risk factors a) Hypertension (Figure S4) Hypertension is a major modifiable CVD risk factor, and its concurrent existence with T2DM leads to an additive and sometimes synergetic effect on CVD risk

Mice on either diet had similar glucose responses under vehicle conditions

Essential supplies: Peptide vial (lyophilized powder) Bacteriostatic water (multi-dose vial) Insulin syringes (1 mL, 100-unit, 29-31 gauge) for drawing doses Larger syringe with needle (3 mL syringe with 18-21 gauge needle) for reconstitution Alcohol swabs or 70% isopropyl alcohol pads Clean, flat work surface Recommended additions: Disposable gloves (nitrile preferred) Sharps container for used needles Pen and label for marking the vial with date and concentration Calculator or the peptide reconstitution calculator Two notes on syringes