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Gradual Dose Increase for Better Tolerance If you experience nausea or other side effects, you may need to increase your dose more slowly than the standard schedule

Plus, real-world adherence data from Blue Health Intelligence and a 2025 study in JAMA Network Open show that roughly 30 percent of patients discontinue within the first month and over half quit within three months with physical discomfort cited as a primary driver. However, with the exception of nausea, Carroll explains that what often tips a patient toward wanting to discontinue the medication isnt one severe symptom

For seniors, he said, the benefits of GLP-1 medications extend far beyond just shedding pounds

The clinician determines, in their independent professional judgment, whether prescription GLP-1 medication is appropriate for you