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doi: 10.1007/s00425-004-1284-8 64 HerbetteS.LenneC.LeblancN.JulienJ.L.DrevetJ.R.Roeckel-DrevetP

This approach aligns with personalized medicine principles that consider biomarker context before starting any supplementation

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To achieve this, we optimized the well-known peptide tripeptide-1 (GHK) by separately grafting the integrin v3-binding motif RGD and the chondroitin sulfate (CS)-binding motif sOtx2 onto it, forming two chimeric targeting peptides, RGD-GHK and sOtx2-GHK