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Recent analyses of the kinetics of formation and decay of a number of GS -derived spin-adducts have identified 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO) and trans -Mito-DEPMPO as STs that form kinetically more stable spin-adducts with GS than DMPO (Fig

Therefore, we explored other avenues for augmenting endogenous glutathione levels and found support in the literature that NAC might be useful in this regard