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Differently, administration of Citrobacter rodentium , a bacterium able to disrupt the epithelial barrier, in NOD mice, could increase intestinal permeability, leading to pancreatic insulitis development [60]

*Correspondence: Hang Lin, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Tissue Engineering and Regenerative Medicine, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers