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About 70% of participants lost at least 5% of their initial body weight after taking the highest dose of Qsymia for 12 months

Lemanceau P, Expert D, Gaymard F, Bakker PAHM, Briat JF

Red flag symptoms requiring urgent medical attention include: Severe, persistent abdominal pain , particularly if located in the upper abdomen and radiating to the back (potential pancreatitis) if pancreatitis is suspected, stop semaglutide immediately and seek urgent medical assessment Persistent vomiting that prevents adequate fluid or medication intake Signs of dehydration such as dizziness, reduced urine output, or dark urine Severe diarrhoea lasting more than 48 hours Blood in vomit or stools Unexplained weight loss beyond what is expected from the medication's therapeutic effect Jaundice (yellowing of skin or eyes), which may indicate gallbladder or liver problems Patients should contact NHS 111 for urgent advice when GP access is not immediately available

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