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Conclusion In conclusion, mounting evidence suggests that certain nutrients, when consumed together, can have a greater efficacy than when consumed alone and have a profound impact on health and longevity

The work was supported by the Monash University Ramaciotti Centre for Cryo-Electron Microscopy, the Bio21 Ian Holmes Imaging Centre (The University of Melbourne) and the Monash eResearch capabilities, including M3 High-performance computing

276 The commonly used hypoglycemic drug metformin is an additional AMPK activator that can inhibit the release of inflammatory cytokines by activating the AMPK pathway, thus exerting an obvious anti-inflammatory effect

they also regulate apoptosis