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When to Switch Medications or Adjust Your Treatment Plan If you've been on semaglutide for 8-12 weeks at an optimal dose and are still gaining weight or experiencing no weight loss, a medication change may be warranted

Intramuscular injections provide rapid B12 replenishment, particularly effective for severe deficiencies

Overall Implications for T2D Treatment and Safety Monitoring Overall, GLP-1RAs were associated with improved glycemic control and reduced renal, metabolic, and cardiovascular risks, without elevating cancer risk, supporting their use in individuals with cardiorenal comorbidities

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