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Here are some key trends in GLP-1 indications and the landmark studies behind them: Type 2 Diabetes Mellitus (T2DM): The foundational indication for GLP-1s, with extensive evidence from trials like LEADER (liraglutide), SUSTAIN-6 (semaglutide), and HARMONY Outcomes (albiglutide) demonstrating significant HbA1c reduction and cardiovascular benefits

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