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Keeping it stored in a dark spot between uses protects its potency throughout the vial's shelf life

It is therefore assumed that transcription from gdhA P2 serves to enhance gdhA expression when the concentration of -ketoglutarate is low, as during invasive disease, both to enhance the activity of the TCA cycle in the catabolic reaction, and to provide L-glutamate for glutathione biosynthesis in the anabolic reaction

The constituents of Bunina bodies are TAR DNA-binding protein 43 (TDP-43), which is present in 97% of ALS patients (Mori et al., 2019)

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