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All of the drugmakers face the prospect of more local competition in China, where Novo's patent on Wegovy's active ingredient semaglutide expires in 2026 and companies like CSPC Pharmaceutical Group and Hangzhou Jiuyuan Genetic Biopharmaceutical Co are developing their own versions of the drug

Selective and membrane-permeable small-molecule inhibitors of NNMT reverse high-fat-diet-induced obesity in mice and remodel adipocyte metabolism (open-access)

Results vary based on individual factors like adherence, metabolism, and lifestyle

By activating both systems simultaneously, Mounjaro has a broader and often more potent effect on metabolism than Ozempic