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1 Introduction Despite decades of intensive research and substantial investmentwith Alzheimers disease alone projected to surpass 1 trillion USD in global cost by 2050 (Nandi et al., 2024), therapeutic progress in neurodegenerative disorders has remained limited, with most clinical approaches continuing to target downstream proteinopathies and yielding only modest effects on disease trajectories (Selkoe and Hardy, 2016

doi: 10.1007/s00125-005-1682-x

Helps to improve skin tone, reduce the appearance of blemishes, and promote a healthy-looking complexion

Involvement of the upper respiratory tract mucosa by primary bronchial melanoma accounts for 89% of all cases of this tumor [32]