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This constant friction not only causes immediate pain but can also lead to chronic inflammation and infection if left untreated

Participants were eligible if we had the following data available at the start of treatment (day 0) and at the follow-up after one year (365 14 days): Before treatment initiation: sex, age (years), body weight (kg), waist circumference (cm), height (cm), body mass index (BMI), systolic and diastolic blood pressure, heart rate, and Edmonton Obesity Staging System (EOSS) score

All descriptions of cellular signaling mechanisms, cytoprotection-associated endpoints, angiogenesis-associated findings, and tissue-level research observations are derived from published in vitro cell-based studies and selected preclinical experimental model research