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Apart from their catalytic role in protecting cells against xenobiotics, GST isoenzymes can function in the detoxification of chemotherapeutic agents, initiating the development of drug resistance through the inactivation of the anticancer compounds via GSH conjugation (Hayes and Pulford 1995

PMID: 9562873

PlexusDx patients begin with lower dosesoften reducing side effects like nauseaand only increase when their body is ready, keeping monthly costs predictable

All personnel involved in the testing procedure were kept unaware of the casecontrol status of the samples, maintaining strict blinding throughout the analysis