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This can be exemplified by malignant melanoma cells, most often harbouring wild-type p53 (Hussein, 2004), which exhibit overexpression of IGF-1R

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Together, these findings highlight that while ACE-inhibitory peptides remain the most extensively studied, peptide-based strategies in cardiovascular diseases potentially extend beyond blood pressure regulation to include vascular repair, plaque stabilization, and endothelial modulation

UV Stress and Melanocytes Ultraviolet radiation can create oxidative stress in skin cells, including melanocytes