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Cisplatins efficacy in liver cancer is limited by resistance and toxicity, but morin hydrate acts as a potent adjuvant to overcome these barriers

A broad spectrum of antidepressant drugs, such as selective serotonin reuptake inhibitors (SSRI), tricyclic antidepressants, selective dopamine reuptake inhibitors, and selective norepinephrine reuptake inhibitors (SNRI), is introduced to change serotonergic, dopaminergic, glutamatergic, or noradrenergic activity levels in the central nervous system (CNS) (Harmer, Duman, and Cowen, 2017)