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But Keytrudas patent is up in 2028, leaving Merck in search of revenue sources amid heated speculation that it might enter the GLP-1 fray via acquisition

We thank Dr Sven Mller, Dr Michael Schulz and Dr Malte Schmick for support in FLIM microscopy and discussion of FLIM-FRET experiments

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The peptide works through several mechanisms: it upregulates growth factor expression (particularly VEGF), promotes angiogenesis (the formation of new blood vessels at injury sites) [5,12] , modulates the nitric oxide system, and supports the FAK-paxillin pathway, which governs cell migration to damaged tissue