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Common semaglutide side effects include nausea, constipation, and diarrheanone of which directly interfere with birth control

The more common events ( 1%) associated with discontinuation and considered to be drug-related (i.e., those events associated with dropout at a rate approximately twice or greater for venlafaxine compared to placebo) included: Commonly Observed Adverse Events in Controlled Clinical Trials The most commonly observed adverse events associated with the use of venlafaxine tablets (incidence of 5% or greater) and not seen at an equivalent incidence among placebo-treated patients (i.e., incidence for venlafaxine tablets at least twice that for placebo), derived from the 1% incidence table below, were asthenia, sweating, nausea, constipation, anorexia, vomiting, somnolence, dry mouth, dizziness, nervousness, anxiety, tremor, and blurred vision as well as abnormal ejaculation/orgasm and impotence in men

Quick answer Zepbound and Mounjaro generally produce the highest average weight loss because they contain tirzepatide, a dual GIP and GLP-1 medication

But dont do anything drastic like stopping the med or crash dieting