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Randomized controlled trial: subcutaneous vs intravenous infliximab CT-P13 maintenance in inflammatory bowel disease

UA also stimulates inducible nitric oxide (NO) synthase (iNOS) gene expression leading to NO-induced -cell dysfunction

To evaluate mRNA stability, transcription was inhibited in cells by treatment with actinomycin D (A9415, Sigma-Aldrich, USA) at a concentration of 10 g/mL