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Current human data can be categorized into three distinct areas: safety and tolerability, metabolic outcomes, and signals for disease modification

Seven additional phase 3 readouts are expected throughout this year, covering a range of conditions including type 2 diabetes, obstructive sleep apnea, chronic low back pain, cardiovascular outcomes, and metabolic dysfunction-associated steatotic liver disease

Research comparing mice treated with GLP-1 medications versus those on calorie restriction with similar weight loss showed the GLP-1 group had substantially greater reductions in liver fat 19

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