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Both are types of combined hormonal contraceptives that deliver estrogen and progestin, just like the combined pill, but through the skin or vaginal lining, not the digestive system

There are many reasons an association can exist, but if the medication is not causing the adverse effect, then those associations are not a directly related safety concern

Proglucagon, a precursor polypeptide, undergoes tissue-specific post-translational processing to yield various biologically active peptides in the pancreas and the gut/brain

These effects are generally mild to moderate and tend to improve over time, especially when dosing is adjusted gradually