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Sin embargo, no todos los ensayos han hallado resultados positivos

A key mediator of neurodegeneration in PD is synuclein overexpression, inflammation, mitochondrial dysfunction, and apoptosis, which are protected from Mucuna pruriens and its constituent compound, ursolic acid

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Furthermore, evidence from epilepsy models indicates that semaglutide can inhibit the activation of the NLRP3 inflammasome, a multiprotein complex responsible for producing inflammatory cytokines such as IL-1 ( 5.2 Enhanced brain metabolism and insulin sensitivity The association between Alzheimers disease (AD) and metabolic dysfunction has led to the characterization of AD as Type 3 diabetes, a condition marked by impaired insulin signaling and glucose utilization in the brain (Zhai et al., 2025)