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Since these drugs have been ins short supply, the manufacturers have little incentive to negotiate lower net prices

Despite this, comparing bovine to human results was important to investigate any differences in the binding of drug molecules in the active site due to the mutation of the selenocysteine to glycine in the human model which had the potential to modulate the interactions that drugs had with this important amino acid residue in the active site

The compounds are cheap, the chemistry is simple and the demand is exploding

(2001) Regional differences in peptide degradation by rat cerebral microvessels: a novel regulatory mechanism for communication between blood and brain