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[1] [7] Other notable effects include injection site reactions beyond pain (erythema, pruritus, induration in 13% of patients), increased heart rate (particularly with liraglutide), gallbladder disease (including gallstones and cholecystitis), and potential dehydration-related acute kidney injury

Peripheral immune cells, such as macrophages and T lymphocytes, can infiltrate the CNS during chronic inflammation

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Sixty-one percent of those whove ever used GLP-1s did to treat a chronic condition like diabetes or heart disease in addition to weight loss, or weight loss alone