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In model experiments employing HEK293 cells in a thiamine-deficient medium, the SLC19A1 variant rs1051266:G exhibits a strong decrease in ThDP efflux compared to the canonic SLC19A1 sequence rs1051266:A

T2DM is the underlying cause of many complications, among which, cardiovascular diseases (CVDs) are mainly responsible for the high rates of morbidity and mortality

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