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Description

Their mechanism gives them two major downstream effects of interest: improved glycemic control and weight reduction (due to appetite reduction + slower gastric emptying) plus other possible metabolic benefits

Leptin is a hormone in the body that manages hunger and feelings of satiety

Appetite and metabolic monitoring

2014, 13:142 GLP-1R Signaling Binding of GLP-1 to GLP-1R triggers a downstream signaling cascade that induces a potent stimulation of glucose induced insulin secretion (GIIS) in pancreatic beta-cells, as well as inhibition of alpha cell glucagon release (6)