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= 14) years, with an HbA1c of 7.4% (0.8%)
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Furthermore, it was demonstrated that GLP-1 receptor plays a regulatory role in the hippocampal function and GLP-1 receptor agonists enhanced GABAA signaling through pre-and postsynaptic mechanisms in rats [57], while exendin-4 therapy normalized cognitive dysfunction and improved impaired hippocampal synaptic plasticity in a mice model of diet-induced obesity [58]
Its molecular structure allows it to span the entire width of a cell membrane anchoring at both the inner and outer surface
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