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Other cell work reports upregulation of collagen synthesis and matrix remodeling enzymes in endometrial stromal cells, implying a role in tissue repair and implantation preparation

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The active fraction was traced to a glycyl-L-histidyl-L-lysine sequence [1]

However, in a similar anatomical study of neurons in the locus coeruleus little or no loss of receptors was found after chronic morphine treatment (Van Bockstaele and Commons, 2001), but acute administration of morphine did induce internalization in the dendrites of neurons in the nucleus accumbens when measured with immuno-electron microscopy (Haberstock-Debic et al., 2003)