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Description

In animal models, it has been shown that rats with acute galactosamine-induced liver failure exhibit regional cerebral edema, indicating that the BBB had lost, at least in part, its barrier function [43]

PMC 1560398

It typically resolves within 2-4 weeks

Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H 2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years