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In the body leucovorin is a biologically active form of folate that exists naturally in food sources, as opposed to folic acid, which is a synthetic form

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Nonetheless, when looking at subgroups meeting the criteria for GHD, mUPD patients showed a significantly better response to rhGH treatment in terms of annual growth rate than deletion patients (0.42 0.26 for del15q vs 0.7 0.21 for mUPD