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Glutathione: The Master Antioxidant Glutathione is a tripeptide made from three amino acids: glutamic acid, cysteine, and glycine

Importantly, peptides do not inhibit the inflammatory phase of healing that is necessary for cellular recruitment and debris clearance

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This creates feed-forward cycles that exacerbate cuproptosis: mtROS oxidize cytosolic GSH, releasing bound Cu, and may upregulate the copper importer CTR1 via pathways such as NF-B, increasing copper influx [65]