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General Wellness, Energy, And Subjective Benefits A survey of 66 long-term intranasal glutathione users (median use ~24 months) reported: 78.8% had an overall positive experience

That said, its superiority over TRT in raising total testosterone appears to be more a result of poor study design than therapeutic efficacy

Its benefit depends heavily on exercise and baseline carnitine status: it is most useful for physically active people, vegetarians, and those with lower dietary intake, and shows little benefit as a standalone, sedentary-use supplement