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Genetic evidence that -arrestins are dispensable for the initiation of 2-adrenergic receptor signaling to ERK

Side-effect management is part of that conversation because nausea, constipation, reflux, and fatigue can all interfere with eating enough protein and maintaining strength

Compounded medication-specific risks include potential variability in formulation, dosing errors associated with self-administration, and quality concerns that the FDA has identified as distinct from risks associated with FDA-approved products