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Figure 8C shows that LZD-treated animals exhibited CD68-positive cells in some renal tubules, moderate CD68-positive reaction in cells of some renal tubules, and a strong CD68-positive reaction in the tubular interstitium appeared in the kidney tissues of male rats of Group 3

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Alcohol & Smoking Both alcohol and cigarette smoke increases free radical production, leading to greater oxidative damage and a higher demand for glutathione

Metabolomics analysis revealed a decrease in glutamine levels in the cancer cells treated with this novel polymer, which led to an upregulation of PD-L1 [172]