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K.DilnashinH.et al (2023)

We also explored the potential for repeated genome editing to further increase plasma Exe4 concentrations for a controllable therapeutic effect

Insulin sensitivity in liver, muscles, and adipose tissue was reduced in subjects with high amounts of hepatic lipids (25.3 3.5%, n = 10) compared to individuals with normal levels of hepatic lipids (3.6 0.5%, n = 10) matched for visceral adipose tissue volume [65]