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However, substantial and sustained cholesterol improvements typically require 5% or greater body weight reduction

Graham Lipkin, Consultant Nephrologist at Queen Elizabeth Hospital Birmingham, "Those who take tacrolimus/ciclosporin should have their levels checked." This additional monitoring is crucial when initiating GLP-1 therapy due to the potential for drug interactions

Both medications work to lower blood sugar, so using them at the same time could increase the risk factors of serious side effects like low blood sugar (hypoglycemia), pancreatitis, and injection site reactions