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Innovent Biologics attached a fatty acid side chain to mazdutide to extend its half-life, allowing once-weekly dosing
Children who benefit most from these medications are those who also receive guidance on nutrition, physical activity, sleep, and long-term behavior changes
PAR2 is activated by several soluble trypsin-like proteases and multiple transmembrane-anchored serine proteases (TMPRSSs) (3335), but their roles in PAR2-mediated metabolic control are incompletely understood
Comparative effectiveness of SGLT2 inhibitors, GLP-1 receptor agonists, DPP-4 inhibitors, and sulfonylureas on risk of kidney outcomes: emulation of a target trial using health care databases
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