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Conversely, several naturally produced antioxidant compounds (e.g., vitamins B12, C, K3, and catechin) were also shown to have a degree of anti-parasitic effect (Paveto et al., 2004

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FSEN1 was identified as a small-molecule inhibitor of FSP1 through chemical screening 118 , and subsequent structural analyses revealed that FSEN1 occupies the substrate-binding pocket of FSP1 in a position analogous to CoQ observed in the enzyme active site, providing structural insight into inhibitor recognition 119