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Although it did not contribute to the establishment of the protein intrinsic disorder concept, this powerful technology rapidly became a popular tool in the IDP field (Ferreon et al., 2010

Two clinical trials are evaluating the safety and efficacy of vedolizumab in the treatment of ICI-induced colitis (NCT04407247, NCT04797325)

Second, in parallel, they exert indirect anti-inflammatory effects through adiposity reduction. According to Jastrzb-Mikiewicz, dermatologists must remember that HS is associated with a significant systemic burden that must be addressed through metabolic treatment approaches