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Comparing mechanisms, benefits, and side effect profiles of both peptides

Fernndez-Dueas V, Taura JJ, Cottet M, Gmez-Soler M, Lpez-Cano M, Ledent C, et al

This creates the conditions for weight regain, the frustrating cycle where patients lose weight on medication and gain it back when they stop

This rebound effect is likely related to physiologic mechanisms triggered by weight reduction that induce compensatory changes in energy balance homeostasis, including increased appetite and reduced energy expenditure [1417]