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The liver, like the intestine, can regulate, at least to some extent, the amount of cholesterol in the VLDL particle by regulating the excretion of cholesterol in bile

Treatment discontinuation also negatively impacted blood sugar control in patients with prediabetes

The addition of methotrexate or another DMARD may also be considered for patients with an inadequate response, although as previously noted, there is little evidence to suggest that methotrexate provides synergistic efficacy in PsA as opposed to RA

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