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On the other hand, the reason why Fas/FasL signaling, caspase-8, and caspase-3 are retained in mature erythrocytes could be to provide the interplay between eryptosis and necroptosis of erythrocytes

DSIP is a research peptide and is not FDA-approved for human use in the United States

2.1.2 Role of SIRT1-p53 in ferroptosis p53 is a multifunctional protein that plays a crucial role in regulating intracellular levels of reactive oxygen species (ROS) and modulating ferroptosis through targeting downstream molecules (Ma et al., 2020)