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Nhng bnh nhn khng tip tc tun th nguyn tc ny sau khi ngng GLP-1 thng c xu hng tng cn tr li nhiu hn, cho thy tm quan trng ca vic duy tr ch n ung kim sot calo lin tc ngay c sau khi ngng thuc

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The data suggest that NADPH production mediated by the atypical PPP is crucial for the rapid maturation of phagolysosomes, protecting macrophages from excessive lysosomal acidification and oxidative stress, thereby enhancing macrophage efferocytosis and improving cellular adaptability to ensure the proper execution of critical homeostatic functions (Wang et al., 2023b) (Figure 2B)