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This adaptation enables Tregs to be more adaptable to low-glucose and/or lactate-rich microenvironments

Changes in blood glucose levelsparticularly rapid fluctuations as glycaemic control improvescan precipitate headaches in susceptible individuals

The early success of these drugs in combating what was considered to be an intractable public health concern has begun to reshape how society is framing obesity as a health issue, leading to ripple effects that are affecting how food is sold and consumed, insurance and workplace wellness policies, and importantly, public attitudes surrounding the veracity of framing obesity as a medical issue that can and should be treated

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