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Intrinsic factor is efficient at absorbing a high percentage of a small dose of B12, but it becomes saturated after a meal containing an above-average amount of B12, and about 4 to 6 hours are required before it can efficiently absorb another dose (Institute of Medicine, 1998)

Four common routes, and how each holds up as of July 2026

Allulose's effects, by contrast, depend on intact metabolic pathways and individual variation in sweetness perception and glucose metabolism

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